1989-1998 Setting up and implementing biochemical assays for infectious diseases, (gyrase inhibitors, ß-lactamase inhibitors, cephalosporins, macrolide of next generation). As an example, active contribution to the caracterization of the mechanism of action caracterization of a new antibacterial, KETEK (thelitromycin), successfully launched in 2002.
1998-2001 Specialization in the development, the miniaturisation and the automation of molecular and cellular assays for high-throughput screening, (HTS). Pioneer in the use of 1536-well microplates in France.
2001-2011 Head of the molecular pharmacology unit, bringing substantial in-house experience in all aspects of assay development, HTS screening, new technologies and innovative equipments.
Project leader of several research projects and management of multiple pharmacological programs, providing enabling tools and expertise for target validation and hit/ lead identification.
2011-2020 Broad range of experience in therapeutic areas such as dermatology, cosmetology, inflammation and antibacterials, combining with a detailed knowledge of various domains: nuclear receptors, GPCRs, ion channels, enzymes, natural products, stem cells, zebrafish, fillers, botulinum toxin, predictive toxicology.
Co-author of over 24 scientific papers and co-inventor of 12 patent applications.